Drug Inducible CRISPR/Cas Systems.
Comput Struct Biotechnol J
; 17: 1171-1177, 2019.
Article
em En
| MEDLINE
| ID: mdl-31462973
4-OHT, 4-Hydroxytamoxifen; ABA, abscisic acid; ADs, activation domains; CIP, chemically induced proximity; CRISPR, clustered, regularly interspaced, short palindromic repeats; Cas, CRISPR-associated protein; CrRNA, CRISPR RNA; DD, destabilizing domain; DHFR, dihydrofolate reductase; ER, Estrogen Receptor; FKBP, FK506-binding protein; FRB, FKBP-rapamycin-binding domain; GA, gibberellin; HIT, Hybrid drug Inducible CRISPR/Cas9 Technologies; Hsp90, heat shock protein 90; LBD, ligand binding domain; LSL, loxP-stop-loxP; MST, multiplex single transcript; NES, nuclear export sequence; NLS, nuclear localization sequence; Ptet, tetO-containing promoter; Sa, Staphylococcus areus; Sp, Streptococcus pyogenes; TMP, trimethoprim; TRE, tetracycline response element; TRE3G, Tet-On 3G protein; TetO, tet operator; TetR, Tet repressor protein; VPR, VP64-P65-Rta; arC9, allosterically regulated Cas9; dCas9, dead Cas9; dCpf1, dead Cpf1; dLbCpf1, Lachnospiraceae bacterium dCpf1; dox, doxycycline; iPSCs, induced pluripotent stem cells; rtTA, reverse-tTA; sgRNA, single guide RNA
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01-internacional
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MEDLINE
Idioma:
En
Revista:
Comput Struct Biotechnol J
Ano de publicação:
2019
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Article