Adaptive hybrid surgery analysis (AHSA) for adjuvant gamma knife radiosurgery treatment of vestibular schwannoma residuals.
Clin Neurol Neurosurg
; 185: 105487, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31476593
OBJECTIVES: Adaptive Hybrid Surgery Analysis (AHSA, Brainlab, Munich, Germany) is a software application generating in real-time conceptual dose plans for tumor residuals but has so far not been assessed for usability in a Gamma Knife (Elekta, Stockholm, Sweden) radiosurgery practice. We aimed to compare AHSA stereotactic radiosurgery dose plans with Leksell Gamma Plan (LGP, Elekta, Stockholm, Sweden) plans for adjuvant radiosurgical treatment of Vestibular Schwannoma (VS) residuals. PATIENTS AND METHODS: In this retrospective comparative study, we compared the automatically calculated AHSA dose plans with clinical LGP treatment plans in 13 patients radiosurgically treated for VS residuals. We first created an LGP template based on our specific constraints to organs at risk (OAR), and a tumor prescription volume coverage of minimum 98%. As most proximal anatomy at risk is not manually contoured in our practice, OARs (i.e. brainstem, optic apparatus and cochlea) in the planning images were automatically segmented in Elements Anatomical Mapping and imported into the AHSA software for re-planning and comparison with the LGP dose plans. RESULTS: There was no significant difference in tumor coverage and conformity index between the LGP and AHSA dose planning data, with the mean and maximal dose to the brainstem slightly higher in the latter. CONCLUSION: The AHSA dose plans for adjuvant radiosurgical treatment of VS residuals were comparable to those of LGP used in our Gamma Knife practice, confirming the usability of AHSA in the management of Vestibular Schwannoma in a Gamma Knife practice.
Palavras-chave
AHS; AHSA; Acoustic; Acoustic neuroma; Adaptive hybrid surgery; Adaptive hybrid surgery analysis; Adjuvant radiosurgery; Elements; Facial preservation; Gamma knife; GammaPlan; Gross total resection; Hearing preservation; IGS; Image-guided surgery; LGP; Navigation; Neuroma; Neurosurgery; Novalis; Post-operative SRS; Radiosurgery; Risks; Sub total resection; Vestibular schwannoma
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Planejamento da Radioterapia Assistida por Computador
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Software
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Neuroma Acústico
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Radiocirurgia
Tipo de estudo:
Etiology_studies
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Observational_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Neurol Neurosurg
Ano de publicação:
2019
Tipo de documento:
Article