Randomized controlled trial of Cerebrolysin's effects on long-term histological outcomes and functional recovery in rats with moderate closed head injury.

Zhang, Yanlu; Chopp, Michael; Zhang, Yi; Zhang, Zheng Gang; Lu, Mei; Zhang, Talan; Wu, Kuan-Han H; Zhang, Li; Mahmood, Asim; Xiong, Ye

Zhang, Yanlu; Chopp, Michael; Zhang, Yi; Zhang, Zheng Gang; Lu, Mei; Zhang, Talan; Wu, Kuan-Han H; Zhang, Li; Mahmood, Asim; Xiong, Ye.

Afiliação

Zhang Y; Departments of1Neurosurgery.
Chopp M; 2Neurology, and.
Zhang Y; 3Department of Physics, Oakland University, Rochester, Michigan.
Zhang ZG; 2Neurology, and.
Lu M; 2Neurology, and.
Zhang T; 4Public Health Sciences, Henry Ford Hospital, Detroit; and.
Wu KH; 4Public Health Sciences, Henry Ford Hospital, Detroit; and.
Zhang L; 4Public Health Sciences, Henry Ford Hospital, Detroit; and.
Mahmood A; 2Neurology, and.
Xiong Y; Departments of1Neurosurgery.

J Neurosurg ; : 1-11, 2019 09 06.

Article em En | MEDLINE | ID: mdl-31491768

Palavras-chave

AD = Alzheimer's disease; APP = amyloid precursor protein; BSA = bovine serum albumin; BrdU = bromodeoxyuridine; CA = cornu ammonis; CC = corpus callosum; CHI = closed head injury; CT = cortex; Cerebrolysin; DCX = doublecortin; DG = dentate gyrus; IP = intraperitoneal/intraperitoneally; MWM = Morris water maze; NOR = novel object recognition; NeuN = neuronal nuclei; PBS = phosphate-buffered saline; TBI = traumatic brain injury; amyloid precursor protein; cognitive function; mNSS = modified neurological severity score; moderate closed head injury; neuroblast; neurogenesis; pNfH = phosphorylated neurofilament heavy subunit; traumatic brain injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: J Neurosurg Ano de publicação: 2019 Tipo de documento: Article

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