LSD acutely impairs working memory, executive functions, and cognitive flexibility, but not risk-based decision-making.

Pokorny, Thomas; Duerler, Patricia; Seifritz, Erich; Vollenweider, Franz X; Preller, Katrin H

Pokorny, Thomas; Duerler, Patricia; Seifritz, Erich; Vollenweider, Franz X; Preller, Katrin H.

Afiliação

Pokorny T; Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
Duerler P; Heffter Research Center Zurich, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
Seifritz E; Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
Vollenweider FX; Heffter Research Center Zurich, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
Preller KH; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.

Psychol Med ; 50(13): 2255-2264, 2020 10.

Article em En | MEDLINE | ID: mdl-31500679

Assuntos

Cognição/efeitos dos fármacos; Função Executiva/efeitos dos fármacos; Dietilamida do Ácido Lisérgico/farmacologia; Memória de Curto Prazo/efeitos dos fármacos; Agonistas do Receptor de Serotonina/farmacologia; Adulto; Tomada de Decisões/efeitos dos fármacos; Método Duplo-Cego; Feminino; Voluntários Saudáveis; Humanos; Ketanserina/farmacologia; Masculino; Testes Neuropsicológicos; Antagonistas da Serotonina/farmacologia; Adulto Jovem

Palavras-chave

5-HT2A receptor; LSD; cognition; executive functions; risk-based decision-making; spatial memory; working memory

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Agonistas do Receptor de Serotonina / Cognição / Função Executiva / Dietilamida do Ácido Lisérgico / Memória de Curto Prazo Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Psychol Med Ano de publicação: 2020 Tipo de documento: Article

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