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Bile salt-coating modulates the macrophage uptake of nanocores constituted by a zidovudine prodrug and enhances its nose-to-brain delivery.
Dalpiaz, Alessandro; Fogagnolo, Marco; Ferraro, Luca; Beggiato, Sarah; Hanuskova, Miriam; Maretti, Eleonora; Sacchetti, Francesca; Leo, Eliana; Pavan, Barbara.
Afiliação
  • Dalpiaz A; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara 19, I-44121 Ferrara, Italy. Electronic address: dla@unife.it.
  • Fogagnolo M; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara 19, I-44121 Ferrara, Italy. Electronic address: marco.fogagnolo@unife.it.
  • Ferraro L; Department of Life Sciences and Biotechnology, University of Ferrara and LTTA Center, Via L. Borsari 46, I-44121 Ferrara, Italy. Electronic address: frl@unife.it.
  • Beggiato S; Department of Life Sciences and Biotechnology, University of Ferrara and LTTA Center, Via L. Borsari 46, I-44121 Ferrara, Italy. Electronic address: sarah.beggiato@unife.it.
  • Hanuskova M; "Enzo Ferrari" Engineering Department, University of Modena and Reggio Emilia, Via Pietro Vivarelli 10, I-41125 Modena, Italy. Electronic address: miriam.hanuskova@unimore.it.
  • Maretti E; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, I-41125 Modena, Italy. Electronic address: eleonora.maretti@unimore.it.
  • Sacchetti F; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, I-41125 Modena, Italy. Electronic address: francesca.sacchetti@unimore.it.
  • Leo E; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, I-41125 Modena, Italy. Electronic address: leoeli27@unimore.it.
  • Pavan B; Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy. Electronic address: pvnbbr@unife.it.
Eur J Pharm Biopharm ; 144: 91-100, 2019 Nov.
Article em En | MEDLINE | ID: mdl-31521715
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Ácidos e Sais Biliares / Pró-Fármacos / Zidovudina / Nanopartículas / Macrófagos / Mucosa Nasal Aspecto: Implementation_research Limite: Animals Idioma: En Revista: Eur J Pharm Biopharm Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Ácidos e Sais Biliares / Pró-Fármacos / Zidovudina / Nanopartículas / Macrófagos / Mucosa Nasal Aspecto: Implementation_research Limite: Animals Idioma: En Revista: Eur J Pharm Biopharm Ano de publicação: 2019 Tipo de documento: Article