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Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
Peng, Yinghua; Zhang, Xiaozheng; Zhang, Tianshu; Grace, Peter M; Li, Hongyuan; Wang, Yibo; Li, Hang; Chen, Hongqian; Watkins, Linda R; Hutchinson, Mark R; Yin, Hang; Wang, Xiaohui.
Afiliação
  • Peng Y; State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, Jilin 130112, China; Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Yantai University, Ya
  • Zhang X; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Zhang T; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Grace PM; Department of Psychology and Neuroscience, and the Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309, USA.
  • Li H; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Wang Y; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Li H; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Chen H; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  • Watkins LR; Department of Psychology and Neuroscience, and the Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309, USA.
  • Hutchinson MR; Discipline of Physiology, Adelaide Medical School, University of Adelaide, South Australia, Australia; ARC Centre of Excellence for Nanoscale Biophotonics, University of Adelaide, South Australia 5000, Australia.
  • Yin H; School of Pharmaceutical Sciences, Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing 100082, China.
  • Wang X; Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Yantai University, Yantai 264005, China; Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China; Department of Applied Chemistry and Eng
Brain Behav Immun ; 82: 432-444, 2019 11.
Article em En | MEDLINE | ID: mdl-31542403

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lovastatina / Receptor 4 Toll-Like / Neuralgia Limite: Animals Idioma: En Revista: Brain Behav Immun Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lovastatina / Receptor 4 Toll-Like / Neuralgia Limite: Animals Idioma: En Revista: Brain Behav Immun Ano de publicação: 2019 Tipo de documento: Article