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Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes.
Endo-Tsukude, Chihiro; Kato, Motohiro; Kaneko, Akihisa; Iida, Satofumi; Kuramoto, Shino; Ishigai, Masaki; Hamada, Akinobu.
Afiliação
  • Endo-Tsukude C; Translational Research Division, Chugai Pharmaceutical Co., Ltd., 2-1-1 Nihonbashi-muromachi, Chuo-ku, Tokyo 103-8324, Japan; Department of Medical Oncology and Translational Research, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-Honmachi, Chuo-ku, Kumamoto 862-0973, Japan
  • Kato M; Research Division, Chugai Pharmaceutical Co., Ltd., 200 Kajiwara, Kamakura, Kanagawa, 247-8530 Japan. Electronic address: katomth@chugai-pharm.co.jp.
  • Kaneko A; Research Division, Chugai Pharmaceutical Co., Ltd., 200 Kajiwara, Kamakura, Kanagawa, 247-8530 Japan. Electronic address: kanekoakh@chugai-pharm.co.jp.
  • Iida S; Translational Research Division, Chugai Pharmaceutical Co., Ltd., 2-1-1 Nihonbashi-muromachi, Chuo-ku, Tokyo 103-8324, Japan. Electronic address: iidastf@chugai-pharm.co.jp.
  • Kuramoto S; Research Division, Chugai Pharmaceutical Co., Ltd., 200 Kajiwara, Kamakura, Kanagawa, 247-8530 Japan. Electronic address: kuramotosn@chugai-pharm.co.jp.
  • Ishigai M; Research Division, Chugai Pharmaceutical Co., Ltd., 200 Kajiwara, Kamakura, Kanagawa, 247-8530 Japan. Electronic address: ishigaimsk@chugai-pharm.co.jp.
  • Hamada A; Department of Medical Oncology and Translational Research, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-Honmachi, Chuo-ku, Kumamoto 862-0973, Japan; National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address: akhamad@ncc.go
Drug Metab Pharmacokinet ; 34(5): 325-333, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31564409
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Citocromo P-450 CYP2C9 / Indutores do Citocromo P-450 CYP2C9 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Drug Metab Pharmacokinet Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Citocromo P-450 CYP2C9 / Indutores do Citocromo P-450 CYP2C9 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Drug Metab Pharmacokinet Ano de publicação: 2019 Tipo de documento: Article