IL-10-producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarction.

Wu, Lan; Dalal, Rajeev; Cao, Connie D; Postoak, J Luke; Yang, Guan; Zhang, Qinkun; Wang, Zhizhang; Lal, Hind; Van Kaer, Luc

Wu, Lan; Dalal, Rajeev; Cao, Connie D; Postoak, J Luke; Yang, Guan; Zhang, Qinkun; Wang, Zhizhang; Lal, Hind; Van Kaer, Luc.

Afiliação

Wu L; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232; lan.wu.1@vumc.org luc.van.kaer@vumc.org.
Dalal R; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Cao CD; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Postoak JL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Yang G; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Zhang Q; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232.
Wang Z; Vanderbilt-NIH Mouse Metabolic Phenotyping Center, Vanderbilt University Medical Center, Nashville, TN 37232.
Lal H; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232.
Van Kaer L; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232; lan.wu.1@vumc.org luc.van.kaer@vumc.org.

Proc Natl Acad Sci U S A ; 116(43): 21673-21684, 2019 10 22.

Article em En | MEDLINE | ID: mdl-31591231

Assuntos

Tecido Adiposo/metabolismo; Linfócitos B/imunologia; Interleucina-10/metabolismo; Infarto do Miocárdio/imunologia; Pericárdio/metabolismo; Tecido Adiposo/citologia; Animais; Quimiocina CXCL13/metabolismo; Feminino; Inflamação/imunologia; Inflamação/patologia; Interleucina-10/genética; Interleucina-33/metabolismo; Contagem de Linfócitos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Infarto do Miocárdio/patologia; Pericárdio/citologia; Regeneração/fisiologia

Palavras-chave

CD5+ B cells; IL-10producing B cells; acute myocardial infarction; inflammation; pericardial adipose tissues

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pericárdio / Linfócitos B / Tecido Adiposo / Interleucina-10 / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article

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