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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.
Huang, Ke; Liang, Qian; Zhou, Ye; Jiang, Lu-Lu; Gu, Wei-Ming; Luo, Ming-Yu; Tang, Ya-Bin; Wang, Yang; Lu, Wei; Huang, Min; Zhang, Sheng-Zhe; Zhuang, Guang-Lei; Dai, Qing; Shen, Qian-Cheng; Zhang, Jian; Lei, Hui-Min; Zhu, Liang; Ye, De-Yong; Chen, Hong-Zhuan; Zhou, Lu; Shen, Ying.
Afiliação
  • Huang K; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Liang Q; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Zhou Y; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Jiang LL; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Gu WM; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Luo MY; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Tang YB; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Wang Y; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Lu W; Key Laboratory of Smart Drug Delivery, Ministry of Education & State Key Laboratory of Molecular Engineering of Polymers, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China.
  • Huang M; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang SZ; State Key Laboratory of Oncogenes and Related Genes, Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
  • Zhuang GL; State Key Laboratory of Oncogenes and Related Genes, Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China.
  • Dai Q; Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
  • Shen QC; State Key Laboratory of Oncogenes and Related Genes, Medicinal Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Zhang J; State Key Laboratory of Oncogenes and Related Genes, Medicinal Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Lei HM; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Zhu L; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China.
  • Ye DY; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Chen HZ; Institute of Interdisciplinary Integrative Biomedical Research, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: hongzhuan_chen@hotmail.com.
  • Zhou L; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: zhoulu@fudan.edu.cn.
  • Shen Y; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Collaborative Innovation Center for Translational Medicine, Shanghai 200025, China. Electronic address: yshen0510@sjtu.edu.cn.
Cell Metab ; 30(6): 1107-1119.e8, 2019 12 03.
Article em En | MEDLINE | ID: mdl-31607564
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Actinas / Carcinoma Pulmonar de Células não Pequenas / Fosfoglicerato Mutase / Inibidores Enzimáticos / Neoplasias Pulmonares / Antracenos Limite: Animals / Female / Humans Idioma: En Revista: Cell Metab Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Actinas / Carcinoma Pulmonar de Células não Pequenas / Fosfoglicerato Mutase / Inibidores Enzimáticos / Neoplasias Pulmonares / Antracenos Limite: Animals / Female / Humans Idioma: En Revista: Cell Metab Ano de publicação: 2019 Tipo de documento: Article