The profiling and identification of the absorbed constituents and metabolites of Naoshuantong capsule in mice biofluids and brain by ultra- fast liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry.

Luo, Lvkeng; Wu, Shuling; Zhu, Xiaoxiao; Su, Weiwei

Luo, Lvkeng; Wu, Shuling; Zhu, Xiaoxiao; Su, Weiwei.

Afiliação

Luo L; Guangzhou Quality R&D Center of Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China.
Wu S; Guangzhou Quality R&D Center of Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China.
Zhu X; Guangzhou Quality R&D Center of Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China.
Su W; Guangzhou Quality R&D Center of Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China. Electronic address: lsssww@126.com.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1129: 121791, 2019 Oct 15.

Article em En | MEDLINE | ID: mdl-31610480

Assuntos

Medicamentos de Ervas Chinesas/administração & dosagem; Medicamentos de Ervas Chinesas/metabolismo; Espectrometria de Massas em Tandem/métodos; Animais; Líquidos Corporais/metabolismo; Encéfalo/metabolismo; Catequina/sangue; Ácido Clorogênico/sangue; Cromatografia Líquida de Alta Pressão/métodos; Ácido Gálico/sangue; Glucosídeos/sangue; Glicosídeos/metabolismo; Hidroxibenzoatos/sangue; Isoflavonas/sangue; Masculino; Medicina Tradicional Chinesa/métodos; Metaboloma; Camundongos; Camundongos Endogâmicos C57BL; Monoterpenos/sangue; Sesquiterpenos/sangue

Palavras-chave

Identification; Metabolites; Naoshuantong capsule; Quadrupole time-of-flight tandem mass spectrometry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2019 Tipo de documento: Article

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