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Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity.
Lesche, Dorothea; Mostafa, Sam; Everall, Ian; Pantelis, Christos; Bousman, Chad A.
Afiliação
  • Lesche D; Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne & Melbourne Health, Melbourne, VIC, Australia.
  • Mostafa S; myDNA Life Australia Limited, South Yarra, VIC, Australia.
  • Everall I; Centre for Medicine Use and Safety, Monash University, Parkville, VIC, Australia.
  • Pantelis C; Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne & Melbourne Health, Melbourne, VIC, Australia.
  • Bousman CA; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Pharmacogenomics J ; 20(2): 192-201, 2020 04.
Article em En | MEDLINE | ID: mdl-31616047
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos / Clozapina / Citocromo P-450 CYP1A2 / Citocromo P-450 CYP2D6 / Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP2C19 Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Revista: Pharmacogenomics J Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos / Clozapina / Citocromo P-450 CYP1A2 / Citocromo P-450 CYP2D6 / Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP2C19 Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Revista: Pharmacogenomics J Ano de publicação: 2020 Tipo de documento: Article