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Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
Taskar, Kunal S; Pilla Reddy, Venkatesh; Burt, Howard; Posada, Maria M; Varma, Manthena; Zheng, Ming; Ullah, Mohammed; Emami Riedmaier, Arian; Umehara, Ken-Ichi; Snoeys, Jan; Nakakariya, Masanori; Chu, Xiaoyan; Beneton, Maud; Chen, Yuan; Huth, Felix; Narayanan, Rangaraj; Mukherjee, Dwaipayan; Dixit, Vaishali; Sugiyama, Yuichi; Neuhoff, Sibylle.
Afiliação
  • Taskar KS; GlaxoSmithKline, DMPK, In Vitro In Vivo Translation, GSK R&D, Ware, UK.
  • Pilla Reddy V; AstraZeneca, Modelling and Simulation, Early Oncology DMPK, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Burt H; Simcyp-Division, Certara UK Ltd., Sheffield, UK.
  • Posada MM; Eli Lilly & Company, Indianapolis, Indiana, USA.
  • Varma M; Pfizer Inc., Groton, Connecticut, USA.
  • Zheng M; Bristol-Myers Squibb Company, Princeton, New Jersey, USA.
  • Ullah M; Roche Innovation Center, Basel, Switzerland.
  • Emami Riedmaier A; AbbVie Inc., North Chicago, Illinois, USA.
  • Umehara KI; Roche Innovation Center, Basel, Switzerland.
  • Snoeys J; Janssen Research and Development, Beerse, Belgium.
  • Nakakariya M; Takeda Pharmaceutical Company Ltd., Kanagawa, Japan.
  • Chu X; Merck Sharp & Dohme Corp., Kenilworth, New Jersey, USA.
  • Beneton M; Servier, Centre-Val de Loire, France.
  • Chen Y; Genentech, San Francisco, California, USA.
  • Huth F; Novartis, Basel, Switzerland.
  • Narayanan R; Shire, Lexington, Massachusetts, USA.
  • Mukherjee D; AbbVie Inc., North Chicago, Illinois, USA.
  • Dixit V; Eisai Inc., Woodliff Lake, New Jersey, USA.
  • Sugiyama Y; Sugiyama Laboratory, Riken, Yokohama, Japan.
  • Neuhoff S; Simcyp-Division, Certara UK Ltd., Sheffield, UK.
Clin Pharmacol Ther ; 107(5): 1082-1115, 2020 05.
Article em En | MEDLINE | ID: mdl-31628859
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Interações Medicamentosas / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Interações Medicamentosas / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2020 Tipo de documento: Article