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Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics.
Klug, Dana M; Tschiegg, Laura; Diaz, Rosario; Rojas-Barros, Domingo; Perez-Moreno, Guiomar; Ceballos, Gloria; García-Hernández, Raquel; Martinez-Martinez, Maria Santos; Manzano, Pilar; Ruiz, Luis Miguel; Caffrey, Conor R; Gamarro, Francisco; Pacanowska, Dolores Gonzalez; Ferrins, Lori; Navarro, Miguel; Pollastri, Michael P.
Afiliação
  • Klug DM; Department of Chemistry & Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Tschiegg L; Department of Chemistry & Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Diaz R; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Rojas-Barros D; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Perez-Moreno G; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Ceballos G; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • García-Hernández R; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Martinez-Martinez MS; Diseases of the Developing World (DDW), Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos 28760, Spain.
  • Manzano P; Diseases of the Developing World (DDW), Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos 28760, Spain.
  • Ruiz LM; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Caffrey CR; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Gamarro F; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Pacanowska DG; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Ferrins L; Department of Chemistry & Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Navarro M; Instituto de Parasitología y Biomedicina "López-Neyra", Consejo Superior de Investigaciones Cientificas (CSIC), Granada 18016, Spain.
  • Pollastri MP; Department of Chemistry & Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
J Med Chem ; 63(5): 2527-2546, 2020 03 12.
Article em En | MEDLINE | ID: mdl-31670951
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma brucei brucei / Tripanossomíase Africana / Indazóis Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma brucei brucei / Tripanossomíase Africana / Indazóis Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Ano de publicação: 2020 Tipo de documento: Article