Effect of a single bout of resistance exercise on zinc-α2-glycoprotein.

ABSTRACT

CONTEXT Resistance exercise training has recently been considered as an effective type of training to increase energy metabolism and insulin sensitivity. However, mechanisms of the resistance training-induced improvements in energy metabolism and insulin sensitivity have not been fully understood. Zinc-α2-glycoprotein (ZAG), which is a novel adipokine, has beneficial effects on energy metabolism and insulin sensitivity. OBJECTIVE: We investigated the effect of a single bout of resistance exercise on the ZAG concentration. METHODS: Nine healthy men were enrolled. They performed a single bout of resistance exercise (bench press and leg press) consisting of 10 repetitions of five sets at 70% of maximum strength with 90-s rests in between sets. Blood samples were obtained before and after acute resistance exercise to measure the ZAG concentration. RESULTS: The serum ZAG concentration significantly increased following acute resistance exercise. CONCLUSION: This result suggests that a single bout of resistance exercise may enhance the ZAG concentration.