The Evaluation of Changes in the Breath Sound Spectrum with Bronchoconstriction and Bronchodilatation in Asthmatic Children.
Tokai J Exp Clin Med
; 44(4): 94-100, 2019 Dec 20.
Article
em En
| MEDLINE
| ID: mdl-31768998
ABSTRACT
OBJECTIVE:
Focusing on the relative-middle sound area of the breath sound spectrum, the relationship between airway changes and breath sounds in asthmatic children was investigated.METHODS:
In Study 1, 77 children (6-16 years old) were included. The breath sound parameters, the ratio of the second area to the third area of the power spectrum (A2/A3) and the ratio of the third area to the fourth area (B3/B4) were evaluated 3 times, before and just after methacholine inhalation and after ß2 agonist inhalation. Other breath sound parameters, the frequency limiting 99% of the power spectrum (F99), the rolloff from 600-1200 Hz (Slope) and the ratio of the third and fourth area to the total area under the curve (A3/AT and B4/AT), and the ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF75 and RPF50), were also evaluated. In Study 2, 91 children (6-16 years old) were included, with evaluations performed twice before and after ß2 a gonist inhalation. Spirography a nd forced o scillation technique were also performed.RESULTS:
In Study 1, A2/A3 and B3/B4 were significantly increased after methacholine inhalation and decreased after ß2 agonist inhalation (p < 0.001, P < 0.001, respectively). In Study 2, A2/A3 and B3/B4 were significantly decreased after ß2 agonist inhalation. These changes in A3/AT and B4/AT were the inverse of those in other spectrum curve indices.CONCLUSIONS:
A2/A3 and B3/B4, indicate the breath sound changes after bronchoconstriction and bronchodilatation. These parameters may be useful for assessing bronchial reversibility in asthmatic children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Broncodilatadores
/
Sons Respiratórios
/
Broncoconstrição
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Tokai J Exp Clin Med
Ano de publicação:
2019
Tipo de documento:
Article