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Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Park, Sang Ho; Ayoub, Alex; Lee, Young-Tae; Xu, Jing; Kim, Hanseong; Zheng, Wei; Zhang, Biao; Sha, Liang; An, Sojin; Zhang, Yang; Cianfrocco, Michael A; Su, Min; Dou, Yali; Cho, Uhn-Soo.
Afiliação
  • Park SH; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Ayoub A; Department of Pathology, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Lee YT; Department of Pathology, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Xu J; Department of Pathology, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Kim H; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Zheng W; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Zhang B; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Sha L; Department of Pathology, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • An S; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Zhang Y; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Cianfrocco MA; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Su M; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Dou Y; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, 48109, USA.
  • Cho US; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, 48109, USA.
Nat Commun ; 10(1): 5540, 2019 12 05.
Article em En | MEDLINE | ID: mdl-31804488
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Nucleossomos / Histona-Lisina N-Metiltransferase / Microscopia Crioeletrônica / Proteína de Leucina Linfoide-Mieloide Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Nucleossomos / Histona-Lisina N-Metiltransferase / Microscopia Crioeletrônica / Proteína de Leucina Linfoide-Mieloide Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2019 Tipo de documento: Article