Rapid Assessment of Water Toxicity by Plasmonic Nanomechanical Sensing.
Anal Chem
; 92(1): 1309-1315, 2020 01 07.
Article
em En
| MEDLINE
| ID: mdl-31820634
ABSTRACT
The ability to rapidly and accurately detect water toxicity is crucial for monitoring water quality and assessing toxic risk, but such detection remains a great challenge. Here, we present a plasmonic nanomechanical sensing (PNMS) system for the rapid assessment of water toxicity. This technique is based on the plasmonic sensing of the nanomechanical movement of single bacterial cells, which could be inhibited upon exposure to potential toxicants. By correlating the amplitude of nanomechanical movement with bacterial activity, we detected a variety of toxic substances in water. The direct readout of bacterial activity via PNMS allowed for a high sensitivity to toxicants in water, thereby enabling us to evaluate the acute toxicological effect of chemical compounds rapidly. The PNMS method is promising for online alerts of water quality safety and for assessing chemical hazards. We anticipate that PNMS is also suitable for a wide range of other applications, including bacterial detection and high-throughput screening of antibacterial materials.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Bacillus thuringiensis
/
Poluentes Químicos da Água
/
Substâncias Perigosas
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Escherichia coli
/
Sistemas Microeletromecânicos
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Antibacterianos
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Anal Chem
Ano de publicação:
2020
Tipo de documento:
Article