The Secretome of Hypoxia Conditioned hMSC Loaded in a Central Depot Induces Chemotaxis and Angiogenesis in a Biomimetic Mineralized Collagen Bone Replacement Material.

Quade, Mandy; Münch, Pina; Lode, Anja; Duin, Sarah; Vater, Corina; Gabrielyan, Anastasia; Rösen-Wolff, Angela; Gelinsky, Michael

Quade, Mandy; Münch, Pina; Lode, Anja; Duin, Sarah; Vater, Corina; Gabrielyan, Anastasia; Rösen-Wolff, Angela; Gelinsky, Michael.

Afiliação

Quade M; Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Münch P; Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Lode A; Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Duin S; Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Vater C; Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Gabrielyan A; University Centre of Orthopaedica and Traumatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Rösen-Wolff A; Department of Pediatrics, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Gelinsky M; Department of Pediatrics, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.

Adv Healthc Mater ; 9(2): e1901426, 2020 01.

Article em En | MEDLINE | ID: mdl-31830380

Assuntos

Indutores da Angiogênese/farmacologia; Substitutos Ósseos/química; Meios de Cultivo Condicionados/química; Células-Tronco Mesenquimais/citologia; Alicerces Teciduais/química; Adulto; Indutores da Angiogênese/química; Materiais Biomiméticos; Regeneração Óssea/fisiologia; Calcificação Fisiológica/efeitos dos fármacos; Hipóxia Celular; Movimento Celular; Células Cultivadas; Colágeno/química; Meios de Cultivo Condicionados/metabolismo; Meios de Cultivo Condicionados/farmacologia; Liofilização; Células Endoteliais da Veia Umbilical Humana; Humanos; Masculino; Células-Tronco Mesenquimais/efeitos dos fármacos

Palavras-chave

homing; hypoxia conditioned stem cell secretome; in situ tissue engineering; mineralized collagen; vascularization

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Meios de Cultivo Condicionados / Substitutos Ósseos / Indutores da Angiogênese / Alicerces Teciduais / Células-Tronco Mesenquimais Tipo de estudo: Guideline Limite: Adult / Humans / Male Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google