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Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis.
Jones, Isabelle C; Espindola, Milena S; Narayanan, Rohan; Coelho, Ana L; Habiel, David M; Boehme, Stefen A; Ly, Tai Wei; Bacon, Kevin B; Hogaboam, Cory M.
Afiliação
  • Jones IC; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
  • Espindola MS; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
  • Narayanan R; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
  • Coelho AL; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
  • Habiel DM; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
  • Boehme SA; Axikin Pharmaceuticals, Inc., San Diego, CA, USA.
  • Ly TW; Axikin Pharmaceuticals, Inc., San Diego, CA, USA.
  • Bacon KB; Axikin Pharmaceuticals, Inc., San Diego, CA, USA.
  • Hogaboam CM; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. cory.hogaboam@cshs.org.
Sci Rep ; 9(1): 19796, 2019 12 24.
Article em En | MEDLINE | ID: mdl-31875033
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MAP Quinase Quinase Quinases / Fibrose Pulmonar Idiopática / Miofibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MAP Quinase Quinase Quinases / Fibrose Pulmonar Idiopática / Miofibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article