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Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Macdonald, Lynn E; Meagher, Karoline A; Franklin, Matthew C; Levenkova, Natasha; Hansen, Johanna; Badithe, Ashok T; Zhong, Maggie; Krueger, Pamela; Rafique, Ashique; Tu, Naxin; Shevchuk, James; Wadhwa, Saurabh; Ehrlich, George; Bautista, Joannie; Grant, Craig; Esau, Lakeisha; Poueymirou, William T; Auerbach, Wojtek; Morton, Lori; Babb, Robert; Chen, Gang; Huang, Tammy; MacDonald, Douglas; Graham, Kenneth; Gurer, Cagan; Voronina, Vera A; McWhirter, John R; Guo, Chunguang; Yancopoulos, George D; Murphy, Andrew J.
Afiliação
  • Macdonald LE; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591 lynn.macdonald@regeneron.com.
  • Meagher KA; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Franklin MC; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Levenkova N; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Hansen J; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Badithe AT; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Zhong M; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Krueger P; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Rafique A; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Tu N; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Shevchuk J; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Wadhwa S; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Ehrlich G; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Bautista J; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Grant C; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Esau L; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Poueymirou WT; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Auerbach W; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Morton L; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Babb R; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Chen G; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Huang T; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • MacDonald D; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Graham K; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Gurer C; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Voronina VA; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • McWhirter JR; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Guo C; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Yancopoulos GD; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
  • Murphy AJ; Regeneron Tech Centers, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Proc Natl Acad Sci U S A ; 117(1): 292-299, 2020 01 07.
Article em En | MEDLINE | ID: mdl-31879340
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Região Variável de Imunoglobulina / Cadeias Pesadas de Imunoglobulinas / Cadeias kappa de Imunoglobulina / Anticorpos / Antígenos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Região Variável de Imunoglobulina / Cadeias Pesadas de Imunoglobulinas / Cadeias kappa de Imunoglobulina / Anticorpos / Antígenos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article