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A Synthetic Human Antibody Antagonizes IL-18Rß Signaling Through an Allosteric Mechanism.
Liu, Shusu; Miersch, Shane; Li, Ping; Bai, Bingxin; Liu, Chunchun; Qin, Wenming; Su, Jie; Huang, Haiming; Pan, James; Sidhu, Sachdev S; Wu, Donghui.
Afiliação
  • Liu S; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Miersch S; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
  • Li P; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China; Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, China.
  • Bai B; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Liu C; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Qin W; National Facility for Protein Science (Shanghai), Shanghai Advanced Research Institute (Zhangjiang Lab), Chinese Academy of Sciences, Shanghai, China.
  • Su J; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Huang H; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada; Shanghai Asian United Antibody Medical Co., Shanghai, China.
  • Pan J; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
  • Sidhu SS; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada. Electron
  • Wu D; Laboratory of Antibody Engineering, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China. Electronic address: wudh@shanghaitech.edu.cn.
J Mol Biol ; 432(4): 1169-1182, 2020 02 14.
Article em En | MEDLINE | ID: mdl-31954129
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-18 Limite: Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-18 Limite: Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2020 Tipo de documento: Article