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Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified.
Breysse, Daniel H; Boone, Ryan M; Long, Cameron M; Merrill, Miranda E; Schaupp, Christopher M; White, Collin C; Kavanagh, Terrance J; Schmidt, Edward E; Merrill, Gary F.
Afiliação
  • Breysse DH; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Boone RM; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Long CM; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Merrill ME; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Schaupp CM; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • White CC; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Kavanagh TJ; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Schmidt EE; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
  • Merrill GF; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon (D.H.B., R.M.B., C.M.L., M.E.M., G.F.M.); Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington (C.M.S., C.C.W., T.J.K.); and Department of Microbiology and Imm
Drug Metab Dispos ; 48(3): 187-197, 2020 03.
Article em En | MEDLINE | ID: mdl-31955137
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Oxirredutases do Álcool / Cardiotoxicidade / Fígado Limite: Animals Idioma: En Revista: Drug Metab Dispos Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Oxirredutases do Álcool / Cardiotoxicidade / Fígado Limite: Animals Idioma: En Revista: Drug Metab Dispos Ano de publicação: 2020 Tipo de documento: Article