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Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.
Kennedy, Susan A; Jarboui, Mohamed-Ali; Srihari, Sriganesh; Raso, Cinzia; Bryan, Kenneth; Dernayka, Layal; Charitou, Theodosia; Bernal-Llinares, Manuel; Herrera-Montavez, Carlos; Krstic, Aleksandar; Matallanas, David; Kotlyar, Max; Jurisica, Igor; Curak, Jasna; Wong, Victoria; Stagljar, Igor; LeBihan, Thierry; Imrie, Lisa; Pillai, Priyanka; Lynn, Miriam A; Fasterius, Erik; Al-Khalili Szigyarto, Cristina; Breen, James; Kiel, Christina; Serrano, Luis; Rauch, Nora; Rukhlenko, Oleksii; Kholodenko, Boris N; Iglesias-Martinez, Luis F; Ryan, Colm J; Pilkington, Ruth; Cammareri, Patrizia; Sansom, Owen; Shave, Steven; Auer, Manfred; Horn, Nicola; Klose, Franziska; Ueffing, Marius; Boldt, Karsten; Lynn, David J; Kolch, Walter.
Afiliação
  • Kennedy SA; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Jarboui MA; Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.
  • Srihari S; Werner Siemens Imaging Center, University of Tübingen, Tübingen, Germany.
  • Raso C; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Bryan K; QIMR-Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.
  • Dernayka L; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Charitou T; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Bernal-Llinares M; Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.
  • Herrera-Montavez C; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Krstic A; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Matallanas D; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Kotlyar M; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Jurisica I; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Curak J; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Wong V; Krembil Research Institute, University Health Network, Toronto, Canada.
  • Stagljar I; Krembil Research Institute, University Health Network, Toronto, Canada.
  • LeBihan T; Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Canada.
  • Imrie L; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
  • Pillai P; Donnelly Centre, University of Toronto, Toronto, Canada.
  • Lynn MA; Department of Biochemistry, University of Toronto, Toronto, Canada.
  • Fasterius E; Department of Molecular Genetics, University of Toronto, Toronto, Canada.
  • Al-Khalili Szigyarto C; Donnelly Centre, University of Toronto, Toronto, Canada.
  • Breen J; Department of Biochemistry, University of Toronto, Toronto, Canada.
  • Kiel C; Department of Molecular Genetics, University of Toronto, Toronto, Canada.
  • Serrano L; Donnelly Centre, University of Toronto, Toronto, Canada.
  • Rauch N; Department of Biochemistry, University of Toronto, Toronto, Canada.
  • Rukhlenko O; Department of Molecular Genetics, University of Toronto, Toronto, Canada.
  • Kholodenko BN; Mediterranean Institute for Life Sciences, Split, Croatia.
  • Iglesias-Martinez LF; Synthetic and Systems Biology, University of Edinburgh, Edinburgh, UK.
  • Ryan CJ; Synthetic and Systems Biology, University of Edinburgh, Edinburgh, UK.
  • Pilkington R; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Cammareri P; EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.
  • Sansom O; School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Shave S; School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Auer M; Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Horn N; School of Biological Sciences, University of Adelaide Bioinformatics Hub, Adelaide, SA, Australia.
  • Klose F; Computational & Systems Biology Program, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.
  • Ueffing M; Systems Biology Ireland, University College Dublin, Dublin, Ireland.
  • Boldt K; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Lynn DJ; Conway Institute, University College Dublin, Dublin, Ireland.
  • Kolch W; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
Nat Commun ; 11(1): 499, 2020 01 24.
Article em En | MEDLINE | ID: mdl-31980649
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Mapas de Interação de Proteínas / Receptores ErbB / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Mapas de Interação de Proteínas / Receptores ErbB / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article