Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-Îµ-caprolactone nano-particles for sustained NSAID delivery.

Rahmani Del Bakhshayesh, Azizeh; Akbarzadeh, Abolfazl; Alihemmati, Alireza; Tayefi Nasrabadi, Hamid; Montaseri, Azadeh; Davaran, Soodabeh; Abedelahi, Ali

Rahmani Del Bakhshayesh, Azizeh; Akbarzadeh, Abolfazl; Alihemmati, Alireza; Tayefi Nasrabadi, Hamid; Montaseri, Azadeh; Davaran, Soodabeh; Abedelahi, Ali.

Afiliação

Rahmani Del Bakhshayesh A; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Akbarzadeh A; Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Alihemmati A; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Tayefi Nasrabadi H; Department of Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Montaseri A; Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Davaran S; Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Abedelahi A; Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Drug Deliv ; 27(1): 269-282, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32009480

Assuntos

Anti-Inflamatórios não Esteroides/administração & dosagem; Produtos Biológicos/administração & dosagem; Colágeno/administração & dosagem; Nanopartículas/administração & dosagem; Piroxicam/administração & dosagem; Caproatos/química; Relação Dose-Resposta a Droga; Portadores de Fármacos; Liberação Controlada de Fármacos; Emulsões; Voluntários Saudáveis; Injeções Intra-Articulares; Lactonas/química; Tamanho da Partícula

Palavras-chave

PCL nanoparticle; Piroxicam; collagen; drug delivery; intra-articular administration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Piroxicam / Anti-Inflamatórios não Esteroides / Colágeno / Nanopartículas Idioma: En Revista: Drug Deliv Ano de publicação: 2020 Tipo de documento: Article

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