Clinical experience of intramuscular immunoglobulin for measles prophylaxis in children: Is it practical?
J Paediatr Child Health
; 56(3): 364-366, 2020 03.
Article
em En
| MEDLINE
| ID: mdl-32043701
ABSTRACT
Measles continues to be a public health concern world-wide. Vulnerable individuals including those in which vaccinations is contraindicated, may be reliant on normal human immunoglobulin (NHIG) prophylaxis in an aim to prevent disease. This paper will summarise and discuss a tertiary paediatric hospital's clinical experience and the practicalities of administering intramuscular (IM) NHIG to paediatric patients as per the current measles prophylaxis guidelines in Australia. Following potential exposure within the emergency department, 17 paediatric patients (0-15 years) were recommended IM NHIG for prophylaxis. The dose of NHIG ranged from 0.6 to 15 mL and required multiple (2-8) injections. Two patients required sedation for staff to safely administer the injections. Staff involved with these cases reported administering multiple injections to paediatric patients to be a traumatising experience. They also expressed views that the injection of large volumes via the IM route was an impractical method of administration. Based on this experience, we recommend intravenous immunoglobulin be considered when large volumes of NHIG are recommended intramuscularly.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
/
4_TD
Base de dados:
MEDLINE
Assunto principal:
Sarampo
Tipo de estudo:
Guideline
Limite:
Child
/
Humans
País/Região como assunto:
Oceania
Idioma:
En
Revista:
J Paediatr Child Health
Ano de publicação:
2020
Tipo de documento:
Article