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The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease.
Monaco, Antonio; Maffia, Veronica; Sorrentino, Nicolina Cristina; Sambri, Irene; Ezhova, Yulia; Giuliano, Teresa; Cacace, Vincenzo; Nusco, Edoardo; De Risi, Maria; De Leonibus, Elvira; Schrader, Thomas; Klärner, Frank-Gerrit; Bitan, Gal; Fraldi, Alessandro.
Afiliação
  • Monaco A; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Maffia V; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Sorrentino NC; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Sambri I; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Ezhova Y; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Giuliano T; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Cacace V; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Nusco E; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • De Risi M; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy; Institute of Cellular Biology and Biochemistry, CNR, Via Ramarini 33, 00015 Monterotondo Scalo, Rome, Italy.
  • De Leonibus E; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy; Institute of Cellular Biology and Biochemistry, CNR, Via Ramarini 33, 00015 Monterotondo Scalo, Rome, Italy.
  • Schrader T; Department of Chemistry, University of Duisburg-Essen, Universitaetsstrasse 7, 45117 Essen, Germany.
  • Klärner FG; Department of Chemistry, University of Duisburg-Essen, Universitaetsstrasse 7, 45117 Essen, Germany.
  • Bitan G; Department of Neurology, David Geffen School of Medicine, Brain Research Institute, University of California, Los Angeles, 635 Charles E. Young Drive South, Los Angeles, CA 90095-7334, USA; Molecular Biology Institute, University of California, Los Angeles, 635 Charles E. Young Drive South, Los Ange
  • Fraldi A; Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy; Department of Translational Medicine, University of Naples "Federico II," Via Sergio Pansini 5, 80131, Naples, Italy. Electronic address: fraldi@tigem.it.
Mol Ther ; 28(4): 1167-1176, 2020 04 08.
Article em En | MEDLINE | ID: mdl-32087148
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organofosfatos / Autofagia / Hidrocarbonetos Aromáticos com Pontes / Mucopolissacaridose III / Doenças Neurodegenerativas Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Mol Ther Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organofosfatos / Autofagia / Hidrocarbonetos Aromáticos com Pontes / Mucopolissacaridose III / Doenças Neurodegenerativas Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Mol Ther Ano de publicação: 2020 Tipo de documento: Article