Divide and Rule: Mitochondrial Fission Regulates Quiescence in Hematopoietic Stem Cells.
Cell Stem Cell
; 26(3): 299-301, 2020 03 05.
Article
em En
| MEDLINE
| ID: mdl-32142657
ABSTRACT
Hematopoietic stem cells (HSCs) remain quiescent to preserve long-term integrity. In this issue of Cell Stem Cell, Hinge et al. (2020) and Liang et al. (2020) demonstrate that HSCs achieve this by regulating mitochondrial fission and lysosomal activity, suppressing glucose uptake, and maintaining healthy punctate mitochondria with low metabolic activity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco Hematopoéticas
/
Dinâmica Mitocondrial
Idioma:
En
Revista:
Cell Stem Cell
Ano de publicação:
2020
Tipo de documento:
Article