Dynamic Augmentation of Left Ventricle and Mitral Valve Function With an Implantable Soft Robotic Device.
JACC Basic Transl Sci
; 5(3): 229-242, 2020 Mar.
Article
em En
| MEDLINE
| ID: mdl-32215347
ABSTRACT
Left ventricular failure is strongly associated with secondary mitral valve regurgitation. Implantable soft robotic devices are an emerging technology that enables augmentation of a native function of a target tissue. We demonstrate the ability of a novel soft robotic ventricular assist device to dynamically augment left ventricular contraction, provide native pulsatile flow, simultaneously reshape the mitral valve apparatus, and eliminate the associated regurgitation in an Short-term large animal model of acute left ventricular systolic dysfunction.
FS, fractional shortening; HF, heart failure; IQR, interquartile range; IVS, interventricular septum; LHF, left heart failure; LV, left ventricular; LVEDP, left ventricular end-diastolic pressure; LVSD, left ventricular systolic dysfunction; MV, mitral valve; MVR, mitral valve regurgitation; RV, right ventricle; SRVAD, soft robotic ventricular assist device; left ventricular systolic dysfunction; mitral valve; secondary mitral regurgitation; soft robotic
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
JACC Basic Transl Sci
Ano de publicação:
2020
Tipo de documento:
Article