Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis.

Ojo, Joseph O; Crynen, Gogce; Algamal, Moustafa; Vallabhaneni, Prashanti; Leary, Paige; Mouzon, Benoit; Reed, Jon M; Mullan, Michael; Crawford, Fiona

Ojo, Joseph O; Crynen, Gogce; Algamal, Moustafa; Vallabhaneni, Prashanti; Leary, Paige; Mouzon, Benoit; Reed, Jon M; Mullan, Michael; Crawford, Fiona.

Afiliação

Ojo JO; Experimental Neuropathology and Proteomic Laboratory, Roskamp Institute, Sarasota, Florida, United States.
Crynen G; James A. Haley Veterans' Hospital, Tampa, Florida, United States.
Algamal M; School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Vallabhaneni P; Experimental Neuropathology and Proteomic Laboratory, Roskamp Institute, Sarasota, Florida, United States.
Leary P; School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Mouzon B; Experimental Neuropathology and Proteomic Laboratory, Roskamp Institute, Sarasota, Florida, United States.
Reed JM; School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Mullan M; Experimental Neuropathology and Proteomic Laboratory, Roskamp Institute, Sarasota, Florida, United States.
Crawford F; Experimental Neuropathology and Proteomic Laboratory, Roskamp Institute, Sarasota, Florida, United States.

ASN Neuro ; 12: 1759091420914768, 2020.

Article em En | MEDLINE | ID: mdl-32241177

Assuntos

Amiloidose/metabolismo; Concussão Encefálica/metabolismo; Encéfalo/metabolismo; Modelos Animais de Doenças; Proteômica/métodos; Tauopatias/metabolismo; Amiloidose/genética; Amiloidose/patologia; Animais; Encéfalo/patologia; Concussão Encefálica/genética; Concussão Encefálica/patologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Tauopatias/genética; Tauopatias/patologia

Palavras-chave

TBI; amyloidosis; molecular pathobiology; neurodegeneration; proteomics; tauopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Concussão Encefálica / Tauopatias / Proteômica / Modelos Animais de Doenças / Amiloidose Limite: Animals Idioma: En Revista: ASN Neuro Ano de publicação: 2020 Tipo de documento: Article

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