A comparative ex vivo permeation evaluation of a novel 5-Fluorocuracil nanoemulsion-gel by topically applied in the different excised rat, goat, and cow skin.
Saudi J Biol Sci
; 27(4): 1024-1040, 2020 Apr.
Article
em En
| MEDLINE
| ID: mdl-32256163
5-FU, 5-Fluorouracil; 5-FU-NE-Gel, 5-Fluorouracil Nanoemulsion Gel; 5-Fluorouracil; ANOVA, Analysis of variance; BCS, Biopharmaceutical Classification System; Cytotoxic activity; DDTC, Diethyldithiocarbamate; DSC, Differential Scanning Calorimetry; Different skin permeation, chemoprevention; Electrospray Ionization, ESI; Er, Enhancement Ratio; FT-IR, Fourier-transform infrared spectroscopy; Kp, Permeability Coefficient; Local accumulation efficiency; NE, Nanoemulsion; Nanoemulsion; Nanoemulsion-gel; PBS, phosphate buffered solution; PDI, Polydispersity Index; RI, Refractive index; SEM, Scanning Electron Microscope; TEM, Transmission Electron Microscope; Transdermal delivery; UHPLC-MS/MS, Ultra high performance liquid chromatography mass spectroscopy and mass spectroscopy; ZP, Zeta Potential
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01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Saudi J Biol Sci
Ano de publicação:
2020
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Article