Delivery of an active lysosomal enzyme using GNeosomes.

Hamill, Kristina M; Wexselblatt, Ezequiel; Tong, Wenyong; Esko, Jeffrey D; Tor, Yitzhak

Hamill, Kristina M; Wexselblatt, Ezequiel; Tong, Wenyong; Esko, Jeffrey D; Tor, Yitzhak.

Afiliação

Hamill KM; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0358, USA. ytor@ucsd.edu.

J Mater Chem B ; 4(35): 5794-5797, 2016 Sep 21.

Article em En | MEDLINE | ID: mdl-32263750

ABSTRACT

ABSTRACT

Two methods for assembling guanidinoneomycin-decorated liposomes are presented and their ability to deliver an active enzyme to the lysosomes and restore enzyme function in diseased cells is compared.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mater Chem B Ano de publicação: 2016 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mater Chem B Ano de publicação: 2016 Tipo de documento: Article