Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics.

Hobson, Chad M; Kern, Megan; O'Brien, E Timothy; Stephens, Andrew D; Falvo, Michael R; Superfine, Richard

Hobson, Chad M; Kern, Megan; O'Brien, E Timothy; Stephens, Andrew D; Falvo, Michael R; Superfine, Richard.

Afiliação

Hobson CM; Department of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Kern M; Department of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
O'Brien ET; Department of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Stephens AD; Biology Department, The University of Massachusetts at Amherst, Amherst, MA 01003, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Falvo MR; Department of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Superfine R; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

Mol Biol Cell ; 31(16): 1788-1801, 2020 07 21.

Article em En | MEDLINE | ID: mdl-32267206

Assuntos

Fenômenos Biomecânicos/fisiologia; Cromatina/fisiologia; Lamina Tipo A/fisiologia; Citoesqueleto de Actina/fisiologia; Actinas/fisiologia; Linhagem Celular; Núcleo Celular/metabolismo; Cromatina/metabolismo; Humanos; Lamina Tipo A/metabolismo; Fenômenos Mecânicos; Microscopia de Força Atômica/métodos; Pressão; Estresse Mecânico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenômenos Biomecânicos / Cromatina / Lamina Tipo A Limite: Humans Idioma: En Revista: Mol Biol Cell Ano de publicação: 2020 Tipo de documento: Article

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