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Recurrent uterine serous carcinoma with a germline pathogenic BRCA2 variant treated using olaparib: A case report.
Inoue, Kayo; Tsubamoto, Hiroshi; Ueda, Tomoko; Tajima, Chihiro; Nakagomi, Nami.
Afiliação
  • Inoue K; Department of Obstetrics and Gynecology, Hyogo College of Medicine, Japan.
  • Tsubamoto H; Department of Obstetrics and Gynecology, Hyogo College of Medicine, Japan.
  • Ueda T; Department of Obstetrics and Gynecology, Hyogo College of Medicine, Japan.
  • Tajima C; Department of Obstetrics and Gynecology, Hyogo College of Medicine, Japan.
  • Nakagomi N; Department of Surgical Pathology, Hyogo College of Medicine, Japan.
Gynecol Oncol Rep ; 32: 100563, 2020 May.
Article em En | MEDLINE | ID: mdl-32300630
A germline pathogenic variant in BRCA2 was secondarily found through genomic sequencing of uterine serous carcinoma. Clinical response to olaparib was observed in recurrent uterine serous carcinoma with a germline BRCA2 mutation. Here, we report, for the first time, a long-term clinical response to olaparib in a patient with uterine serous carcinoma and a germline pathogenic BRCA2 variant.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Ano de publicação: 2020 Tipo de documento: Article