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Local management of preinvasive and clinical T1-3 penile cancer: utilization of diverse treatment modalities.
Menon, Hari; Patel, Roshal R; Ludmir, Ethan B; Muralidhar, Vinayak; Cushman, Taylor R; Amini, Arya; Seyedin, Steven N; Nguyen, Paul L; Verma, Vivek.
Afiliação
  • Menon H; University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.
  • Patel RR; Albany Medical College, Albany, NY 12208, USA.
  • Ludmir EB; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, TX 77030, USA.
  • Muralidhar V; Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, TX 77030, USA.
  • Cushman TR; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham & Women's Hospital, Boston, MA 02215, USA.
  • Amini A; University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.
  • Seyedin SN; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Nguyen PL; Department of Radiation Oncology, University of Iowa Hospital & Clinics, Iowa City, IA 52242, USA.
  • Verma V; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham & Women's Hospital, Boston, MA 02215, USA.
Future Oncol ; 16(14): 955-960, 2020 May.
Article em En | MEDLINE | ID: mdl-32301342
Aim: To explore management trends in preinvasive and cT1-T3 penile cancer. Materials & methods: The National Cancer Database was queried (2004-2013) for cT1-T3 M0 penile cancer with specified nonpalliative surgical techniques and histologies (n = 5,728). Results: Local excision (39%) and partial penectomy (38%) were most commonly utilized. Patients with cTis/Ta or cT1 disease more often received nonpenectomy approaches (p < 0.05); cT2-T3 cases more likely underwent penectomy (p < 0.001). No survival differences were observed between penectomy (49.3 months) and nonpenectomy approaches (50.3 months) in the overall cohort (p = 0.107) and when stratifying by T-stage (p > 0.20 for all). Conclusion: This study provides contemporary insight into the landscape for management of this rare disease and can serve as a benchmark for future evaluation of treatment trends.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Penianas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Future Oncol Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Penianas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Future Oncol Ano de publicação: 2020 Tipo de documento: Article