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Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression.
Weng, Mei-Lin; Chen, Wan-Kun; Chen, Xiang-Yuan; Lu, Hong; Sun, Zhi-Rong; Yu, Qi; Sun, Peng-Fei; Xu, Ya-Jun; Zhu, Min-Min; Jiang, Nan; Zhang, Jin; Zhang, Jian-Ping; Song, Yuan-Lin; Ma, Duan; Zhang, Xiao-Ping; Miao, Chang-Hong.
Afiliação
  • Weng ML; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Chen WK; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Chen XY; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
  • Lu H; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Sun ZR; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Yu Q; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Sun PF; Department of Radiation Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Xu YJ; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Zhu MM; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Jiang N; Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Zhang J; Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, Collaborative Innovation Center of Genetics and Development, Institutes of Biomedical Science, School of Basic Medical Science, Fudan University, Shanghai, 200032, China.
  • Zhang JP; Institute of Biomedical Science, Fudan University, Shanghai, 200032, China.
  • Song YL; Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, Collaborative Innovation Center of Genetics and Development, Institutes of Biomedical Science, School of Basic Medical Science, Fudan University, Shanghai, 200032, China.
  • Ma D; Institute of Biomedical Science, Fudan University, Shanghai, 200032, China.
  • Zhang XP; Institute of Modern Physics, Fudan University; Department of Nuclear Medicine, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Miao CH; Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Nat Commun ; 11(1): 1869, 2020 04 20.
Article em En | MEDLINE | ID: mdl-32313017
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farnesil-Difosfato Farnesiltransferase / Neoplasias Colorretais / Jejum / Neoplasias do Colo / Proteínas Proto-Oncogênicas c-akt / Subunidade alfa do Fator 1 Induzível por Hipóxia / Serina-Treonina Quinases TOR / Glicólise Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farnesil-Difosfato Farnesiltransferase / Neoplasias Colorretais / Jejum / Neoplasias do Colo / Proteínas Proto-Oncogênicas c-akt / Subunidade alfa do Fator 1 Induzível por Hipóxia / Serina-Treonina Quinases TOR / Glicólise Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article