Tuberculosis trends in a hot-spot region in Paris, France.
Int J Tuberc Lung Dis
; 24(4): 428-435, 2020 04 01.
Article
em En
| MEDLINE
| ID: mdl-32317068
ABSTRACT
SETTING:
Tuberculosis (TB) incidence is declining overall in France, but not in Paris where some areas remain relative hot spots for TB.OBJECTIVES:
To obtain a better knowledge of local TB epidemiology in order to facilitate control measures.DESIGN:
Analysis of demographic data of TB patients diagnosed at the Bichat-Claude Bernard Hospital from 2007 to 2016, with spoligotyping of Mycobacterium tuberculosis complex isolates.RESULTS:
During the study period, 1096 TB patients were analysed. The incidence of TB diagnosis was stable, averaging 115 patients per year, predominantly males (71%), foreign-born (81%), with pulmonary TB (77%) and negative HIV serology (88%). The mean age of foreign-born TB patients decreased over the study period, most significantly in recent arrivals in France, whose average age decreased by two years (P = 0.001). The time period between arrival in France and being diagnosed with active TB decreased annually significantly by 0.75 years (P = 0.02). The proportion of L4.6.2/Cameroon and L2/Beijing sub-lineages increased annually by 0.7% (P < 0.05). Multi-drug resistant strains, representing 4% of all strains, increased annually by 0.75% (P = 0.03)CONCLUSION:
The number of TB patients remained high in northern Paris and the surrounding suburbs, suggesting the need for increased control measures.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Tuberculose
/
Tuberculose Resistente a Múltiplos Medicamentos
/
Mycobacterium tuberculosis
Tipo de estudo:
Diagnostic_studies
Limite:
Child, preschool
/
Humans
/
Male
País/Região como assunto:
Africa
/
Asia
/
Europa
Idioma:
En
Revista:
Int J Tuberc Lung Dis
Ano de publicação:
2020
Tipo de documento:
Article