Development of new self-assembled cationic amino liposomes for efficient gene delivery.
Biomater Sci
; 8(11): 3021-3025, 2020 Jun 07.
Article
em En
| MEDLINE
| ID: mdl-32322846
ABSTRACT
A library of 83 structurally diverse cationic amino liposomes is rationally designed and parallelly synthesized for the transfection of plasmid DNA and siRNA. Our designed self-assembled liposomes not only exhibit excellent transfection efficiency in HEK 293T cells and mouse embryonic stem cells, but also show low cytotoxicity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Técnicas de Transferência de Genes
/
RNA Interferente Pequeno
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biomater Sci
Ano de publicação:
2020
Tipo de documento:
Article