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Biological sex and DNA repair deficiency drive Alzheimer's disease via systemic metabolic remodeling and brain mitochondrial dysfunction.
Demarest, Tyler G; Varma, Vijay R; Estrada, Darlene; Babbar, Mansi; Basu, Sambuddha; Mahajan, Uma V; Moaddel, Ruin; Croteau, Deborah L; Thambisetty, Madhav; Mattson, Mark P; Bohr, Vilhelm A.
Afiliação
  • Demarest TG; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Varma VR; Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Estrada D; Unit of Clinical and Translational Neuroscience, Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
  • Babbar M; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Basu S; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Mahajan UV; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Moaddel R; Unit of Clinical and Translational Neuroscience, Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
  • Croteau DL; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Thambisetty M; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
  • Mattson MP; Unit of Clinical and Translational Neuroscience, Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
  • Bohr VA; Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
Acta Neuropathol ; 140(1): 25-47, 2020 07.
Article em En | MEDLINE | ID: mdl-32333098
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Caracteres Sexuais / Distúrbios no Reparo do DNA / Doença de Alzheimer / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Caracteres Sexuais / Distúrbios no Reparo do DNA / Doença de Alzheimer / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2020 Tipo de documento: Article