Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids.

Lu, Zeyu; Paolella, Brenton R; Truex, Nicholas L; Loftis, Alexander R; Liao, Xiaoli; Rabideau, Amy E; Brown, Meredith S; Busanovich, John; Beroukhim, Rameen; Pentelute, Bradley L

Lu, Zeyu; Paolella, Brenton R; Truex, Nicholas L; Loftis, Alexander R; Liao, Xiaoli; Rabideau, Amy E; Brown, Meredith S; Busanovich, John; Beroukhim, Rameen; Pentelute, Bradley L.

Afiliação

Lu Z; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Paolella BR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02139, United States.
Truex NL; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Loftis AR; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Liao X; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Rabideau AE; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Brown MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02139, United States.
Busanovich J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02139, United States.
Beroukhim R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02139, United States.
Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

ACS Chem Biol ; 15(6): 1358-1369, 2020 06 19.

Article em En | MEDLINE | ID: mdl-32348107

Assuntos

Antígenos de Bactérias/química; Toxinas Bacterianas/química; Portadores de Fármacos/química; Oligonucleotídeos Antissenso/administração & dosagem; Ácidos Nucleicos Peptídicos/administração & dosagem; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Sistemas de Liberação de Medicamentos; Terapia Genética; Humanos; Neoplasias/genética; Neoplasias/terapia; Oligonucleotídeos Antissenso/farmacologia; Ácidos Nucleicos Peptídicos/farmacologia; Fosfoproteínas/genética; Fatores de Processamento de RNA/genética

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Portadores de Fármacos / Oligonucleotídeos Antissenso / Ácidos Nucleicos Peptídicos / Antígenos de Bactérias Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2020 Tipo de documento: Article

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