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Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study.
Cavo, Michele; Gay, Francesca; Beksac, Meral; Pantani, Lucia; Petrucci, Maria Teresa; Dimopoulos, Meletios A; Dozza, Luca; van der Holt, Bronno; Zweegman, Sonja; Oliva, Stefania; van der Velden, Vincent H J; Zamagni, Elena; Palumbo, Giuseppe A; Patriarca, Francesca; Montefusco, Vittorio; Galli, Monica; Maisnar, Vladimir; Gamberi, Barbara; Hansson, Markus; Belotti, Angelo; Pour, Ludek; Ypma, Paula; Grasso, Mariella; Croockewit, Alexsandra; Ballanti, Stelvio; Offidani, Massimo; Vincelli, Iolanda D; Zambello, Renato; Liberati, Anna Marina; Andersen, Niels Frost; Broijl, Annemiek; Troia, Rossella; Pascarella, Anna; Benevolo, Giulia; Levin, Mark-David; Bos, Gerard; Ludwig, Heinz; Aquino, Sara; Morelli, Anna Maria; Wu, Ka Lung; Boersma, Rinske; Hajek, Roman; Durian, Marc; von dem Borne, Peter A; Caravita di Toritto, Tommaso; Zander, Thilo; Driessen, Christoph; Specchia, Giorgina; Waage, Anders; Gimsing, Peter.
Afiliação
  • Cavo M; Seràgnoli Institute of Hematology, Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, S Orsola Malpighi Hospital, Bologna, Italy. Electronic address: michele.cavo@unibo.it.
  • Gay F; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
  • Beksac M; Department of Hematology, Ankara University School of Medicine, Ankara, Turkey.
  • Pantani L; Seràgnoli Institute of Hematology, Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, S Orsola Malpighi Hospital, Bologna, Italy.
  • Petrucci MT; Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
  • Dimopoulos MA; Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Dozza L; Seràgnoli Institute of Hematology, Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, S Orsola Malpighi Hospital, Bologna, Italy.
  • van der Holt B; Department of Trials and Statistics-HOVON Data Centre, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
  • Zweegman S; Department of Hematology, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Oliva S; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
  • van der Velden VHJ; Department of Immunology, Erasmus MC, Rotterdam, Netherlands.
  • Zamagni E; Seràgnoli Institute of Hematology, Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, S Orsola Malpighi Hospital, Bologna, Italy.
  • Palumbo GA; Dipartimento di Science Mediche Chirurgiche e Tecnologie Avanzate "GF Ingrassia", Università degli Studi di Catania, Catania, Italy.
  • Patriarca F; Clinical Hematology and Bone Marrow Transplant Centre, S Maria della Misericordia University Hospital, DAME, University of Udine, Udine, Italy.
  • Montefusco V; Hematology Department, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Galli M; Hematology and Bone Marrow Transplant Unit, ASST-Papa Giovanni XXIII, Bergamo, Italy.
  • Maisnar V; 4th Department of Internal Medicine-Hematology, Charles University Hospital and Faculty of Medicine, Hradec Kralove, Czech Republic.
  • Gamberi B; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
  • Hansson M; Skane University Hospital, Lund, Sweden.
  • Belotti A; SC Ematologia e Dipartimento di Oncologia Clinica, AO Spedali Civili, Brescia, Italy.
  • Pour L; University Hospital Brno, Brno, Czech Republic.
  • Ypma P; Department of Hematology, Haga Hospital, The Hague, Netherlands.
  • Grasso M; SC Ematologia, Azienda Ospedaliera S Croce-Carle, Cuneo, Italy.
  • Croockewit A; Department of Hematology, Radboud University Medical Centre, Nijmegen, Netherlands.
  • Ballanti S; Reparto di Ematologia con TMO, Ospedale Santa Maria della Misericordia, Perugia, Italy.
  • Offidani M; Clinica di Ematologia, AOU Ospedali Riuniti di Ancona, Ancona, Italy.
  • Vincelli ID; Division of Haematology, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy.
  • Zambello R; Hematology, Azienda Ospedaliera di Padova, Padua, Italy.
  • Liberati AM; Faculty of Medicine, Università degli Studi di Perugia, Perugia, Italy.
  • Andersen NF; Department of Haematology, Aarhus University Hospital, Aarhus, Denmark.
  • Broijl A; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
  • Troia R; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
  • Pascarella A; Hematology Unit, Ospedale dell'Angelo, Mestre, Venice, Italy.
  • Benevolo G; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
  • Levin MD; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands.
  • Bos G; Department of Haematology, Maastricht University Medical Center, Maastricht, Netherlands.
  • Ludwig H; Wilhelminen Cancer Research Institute, Wilhelminenspital, Vienna, Austria.
  • Aquino S; Ematologia e Centro Trapianti, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Morelli AM; Clinical Hematology, Department of Hematology, Transfusion Medicine and Biotechnology, "Spirito Santo" Civic Hospital, Pescara, Italy.
  • Wu KL; Department of Hematology, ZNA Stuivenberg, Antwerp, Belgium.
  • Boersma R; Department of Internal Medicine, Amphia Hospital Breda, Breda, Netherlands.
  • Hajek R; Department of Hematooncology, University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic.
  • Durian M; University Hospital and Faculty of Medicine, Hradec Kralove, Czech Republic.
  • von dem Borne PA; Department of Hematology, Leiden University Medical Center, Leiden, Netherlands.
  • Caravita di Toritto T; UOSD Ematologia ASL Roma 1, Rome, Italy.
  • Zander T; Department Oncology/Hematology, Kantonsspital, Lucerne, Switzerland.
  • Driessen C; Department Oncology/Hematology, Kantonsspital, St Gallen, Switzerland.
  • Specchia G; Hematology, University Aldo Moro, Bari, Italy.
  • Waage A; Department of Hematology, St Olavs Hospital and Norwegian University of Science and Technology, Trondheim, Norway.
  • Gimsing P; Department of Haematology, University of Copenhagen, Copenhagen, Denmark.
Lancet Haematol ; 7(6): e456-e468, 2020 Jun.
Article em En | MEDLINE | ID: mdl-32359506
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND / 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Transplante Autólogo / Transplante de Células-Tronco Hematopoéticas / Quimioterapia de Consolidação / Mieloma Múltiplo Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline Idioma: En Revista: Lancet Haematol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND / 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Transplante Autólogo / Transplante de Células-Tronco Hematopoéticas / Quimioterapia de Consolidação / Mieloma Múltiplo Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline Idioma: En Revista: Lancet Haematol Ano de publicação: 2020 Tipo de documento: Article