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Fine-scale population genetic structure of dengue mosquito vector, Aedes aegypti, in Metropolitan Manila, Philippines.
Carvajal, Thaddeus M; Ogishi, Kohei; Yaegeshi, Sakiko; Hernandez, Lara Fides T; Viacrusis, Katherine M; Ho, Howell T; Amalin, Divina M; Watanabe, Kozo.
Afiliação
  • Carvajal TM; Center for Marine Environmental Studies (CMES)-Ehime University, Matsuyama, Japan.
  • Ogishi K; Department of Civil and Environmental Engineering-Ehime University, Matsuyama, Japan.
  • Yaegeshi S; Biology Department-De La Salle University, Taft Ave Manila, Philippines.
  • Hernandez LFT; Biological Control Research Unit, Center for Natural Science and Environmental Research-De La Salle University, Taft Ave Manila, Philippines.
  • Viacrusis KM; Department of Civil and Environmental Engineering-Ehime University, Matsuyama, Japan.
  • Ho HT; Department of Civil and Environmental Engineering-Ehime University, Matsuyama, Japan.
  • Amalin DM; Department of Civil and Environmental Engineering, University of Yamanashi, Kofu, Japan.
  • Watanabe K; Department of Civil and Environmental Engineering-Ehime University, Matsuyama, Japan.
PLoS Negl Trop Dis ; 14(5): e0008279, 2020 05.
Article em En | MEDLINE | ID: mdl-32365059
Dengue is a highly endemic disease in Southeast Asia and is transmitted primarily by the mosquito, Aedes aegypti. The National Capital Region (NCR) of the Philippines, or Metropolitan Manila, is a highly urbanized area that is greatly affected by this arboviral disease. Urbanization has been shown to increase the dispersal of this mosquito vector. For this reason, we conducted a fine-scale population genetic study of Ae. aegypti in this region. We collected adult Ae. aegypti mosquitoes (n = 526 individuals) within the region (n = 21 study areas) and characterized the present population structure and the genetic relatedness among mosquito populations. We genotyped 11 microsatellite loci from all sampled mosquito individuals and analyzed their genetic diversity, differentiation and structure. The results revealed low genetic differentiation across mosquito populations which suggest high gene flow and/or weak genetic drift among mosquito populations. Bayesian analysis indicated multiple genetic structures (K = 3-6), with no clear genetically distinct population structures. This result implies the passive or long-distance dispersal capability nature Ae. aegypti possibly through human-mediated transportation. The constructed dendrogram in this study describes the potential passive dispersal patterns across Metropolitan Manila. Furthermore, spatial autocorrelation analysis showed the limited and active dispersal capability (<1km) of the mosquito vector. Our findings are consistent with previous studies that investigated the genetic structure and dual (active and passive) dispersal capability of Ae. aegypti in a fine-scale highly urbanized area.
Assuntos

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Aedes / Mosquitos Vetores / Genótipo Limite: Animals País/Região como assunto: Asia Idioma: En Revista: PLoS Negl Trop Dis Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Aedes / Mosquitos Vetores / Genótipo Limite: Animals País/Região como assunto: Asia Idioma: En Revista: PLoS Negl Trop Dis Ano de publicação: 2020 Tipo de documento: Article