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APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Montagne, Axel; Nation, Daniel A; Sagare, Abhay P; Barisano, Giuseppe; Sweeney, Melanie D; Chakhoyan, Ararat; Pachicano, Maricarmen; Joe, Elizabeth; Nelson, Amy R; D'Orazio, Lina M; Buennagel, David P; Harrington, Michael G; Benzinger, Tammie L S; Fagan, Anne M; Ringman, John M; Schneider, Lon S; Morris, John C; Reiman, Eric M; Caselli, Richard J; Chui, Helena C; Tcw, Julia; Chen, Yining; Pa, Judy; Conti, Peter S; Law, Meng; Toga, Arthur W; Zlokovic, Berislav V.
Afiliação
  • Montagne A; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Nation DA; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Sagare AP; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Barisano G; Department of Psychological Science, University of California, Irvine, Irvine, CA, USA.
  • Sweeney MD; Institute for Memory Disorders and Neurological Impairments, University of California, Irvine, Irvine, CA, USA.
  • Chakhoyan A; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Pachicano M; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Joe E; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Nelson AR; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • D'Orazio LM; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Buennagel DP; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Harrington MG; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Benzinger TLS; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Fagan AM; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Ringman JM; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Schneider LS; Huntington Medical Research Institutes, Pasadena, CA, USA.
  • Morris JC; Huntington Medical Research Institutes, Pasadena, CA, USA.
  • Reiman EM; Department of Radiology, Washington University School of Medicine, St Louis, MO, USA.
  • Caselli RJ; The Hope Center for Neurodegenerative Disorders, Washington University School of Medicine, St Louis, MO, USA.
  • Chui HC; The Hope Center for Neurodegenerative Disorders, Washington University School of Medicine, St Louis, MO, USA.
  • Tcw J; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
  • Chen Y; The Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St Louis, MO, USA.
  • Pa J; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Conti PS; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Law M; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Toga AW; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Zlokovic BV; Department of Psychiatry and Behavioral Sciences, University of Southern California, Los Angeles, CA, USA.
Nature ; 581(7806): 71-76, 2020 05.
Article em En | MEDLINE | ID: mdl-32376954
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Apolipoproteína E4 / Disfunção Cognitiva Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Apolipoproteína E4 / Disfunção Cognitiva Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article