[Cardiac Surgery for Mitral Regurgitation Associated with Essential Thrombocythemia].
Kyobu Geka
; 73(5): 353-357, 2020 May.
Article
em Ja
| MEDLINE
| ID: mdl-32398392
ABSTRACT
An 80-year-old woman with essential thrombocythemia was diagnosed with severe mitral regurgitation and moderate tricuspid regurgitation. Preoperatively, she had been treated with hydroxycarbamide and low-dose aspirin since her platelet count was high( 96.2×104/µl). After the platelet count was reduced to 46.2×104/µl, she underwent mitral valve repair and tricuspid valve annuloplasty. Atypical heparin resistance was noted intraoperatively. After initial heparin infusion, the activated clotting time(ACT) increased as expected. However, it decreased after initiation of cardiopulmonary bypass, despite additional heparin infusion and heparin concentration maintenance. A correlation between platelet factor 4 and heparin resistance was suggested. On discharge, she had no complications. We should consider the possibility of heparin resistance in essential thrombocythemia even when platelet count is adequately controlled.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Insuficiência da Valva Tricúspide
/
Anuloplastia da Valva Mitral
/
Trombocitemia Essencial
/
Insuficiência da Valva Mitral
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Aged80
/
Female
/
Humans
Idioma:
Ja
Revista:
Kyobu Geka
Ano de publicação:
2020
Tipo de documento:
Article