Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.

Mais, Christopher-Nils; Hermann, Lucas; Altegoer, Florian; Seubert, Andreas; Richter, Alexandra A; Wernersbach, Isa; Czech, Laura; Bremer, Erhard; Bange, Gert

Mais, Christopher-Nils; Hermann, Lucas; Altegoer, Florian; Seubert, Andreas; Richter, Alexandra A; Wernersbach, Isa; Czech, Laura; Bremer, Erhard; Bange, Gert.

Afiliação

Mais CN; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Chemistry, Marburg, Germany.
Hermann L; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Biology, Marburg, Germany.
Altegoer F; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Chemistry, Marburg, Germany.
Seubert A; Philipps-University Marburg, Faculty of Chemistry, Marburg, Germany.
Richter AA; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Biology, Marburg, Germany.
Wernersbach I; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Chemistry, Marburg, Germany.
Czech L; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Biology, Marburg, Germany.
Bremer E; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Biology, Marburg, Germany. Electronic address: bremer@staff.uni-marburg.de.
Bange G; Philipps-University Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Chemistry, Marburg, Germany. Electronic address: gert.bange@synmikro.uni-marburg.de.

J Biol Chem ; 295(27): 9087-9104, 2020 07 03.

Article em En | MEDLINE | ID: mdl-32404365

Assuntos

Diamino Aminoácidos/metabolismo; Osmorregulação/fisiologia; Proteínas de Bactérias/metabolismo; Domínio Catalítico; Regulação Bacteriana da Expressão Gênica/genética; Halomonas/metabolismo; Histona Desacetilases/metabolismo; Histona Desacetilases/ultraestrutura; Hidrolases/metabolismo; Hidrolases/ultraestrutura; Chaperonas Moleculares/metabolismo; Família Multigênica; Rhodobacteraceae/metabolismo

Palavras-chave

EutD; EutE; X-ray crystallography; catalytic mechanism; chemical chaperone; deacetylase; ectoine; enzyme catalysis; enzyme structure; hydrolase; metalloenzyme; microbial community; pyrimidine; salt stress; structural biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osmorregulação / Diamino Aminoácidos Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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