Breakthroughs in the Use of Inositols for Assisted Reproductive Treatment (ART).
Trends Endocrinol Metab
; 31(8): 570-579, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32418772
ABSTRACT
It is well known that myo-inositol (MI) and D-chiro-inositol (DCI) are insulin-sensitizing agents, and MI is of proven utility in polycystic ovary syndrome (PCOS). In addition, MI plays a pivotal role in the physiology of reproduction, and has beneficial effects on the development of oocytes, spermatozoa, and embryos. By contrast, DCI has little effect on spermatozoa, but high concentrations in the ovary can negatively affect the quality of oocytes and the blastocyst. Overall, the evidence in the literature supports the beneficial effects of MI in both female and male reproduction, warranting clinical use of MI in assisted reproductive treatment (ART).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Técnicas de Reprodução Assistida
/
Inositol
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Trends Endocrinol Metab
Ano de publicação:
2020
Tipo de documento:
Article