An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds.
Chem Commun (Camb)
; 56(50): 6818-6821, 2020 Jun 23.
Article
em En
| MEDLINE
| ID: mdl-32432281
ABSTRACT
Herein, we describe the development of a simple, high yielding and stereocontrolled strategy for the synthesis of a series of triazolopiperazines and other biologically relevant fused scaffolds from optically active amino acids. This route was applied to the synthesis of 22 scaffolds containing new, previously inaccessible vectors and used to access a novel analogue of ganaplacide.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Ano de publicação:
2020
Tipo de documento:
Article