Selective Photoinduced Reduction of Nitroarenes to N-Arylhydroxylamines.
Org Lett
; 22(11): 4339-4343, 2020 06 05.
Article
em En
| MEDLINE
| ID: mdl-32453579
ABSTRACT
We report the selective photoinduced reduction of nitroarenes to N-arylhydroxylamines. The present methodology facilitates this transformation in the absence of catalyst or additives and uses only light and methylhydrazine. This noncatalytic photoinduced transformation proceeds with a broad scope, excellent functional-group tolerance, and high yields. The potential of this protocol reflects on the selective and straightforward conversion of two general antibiotics, azomycin and chloramphenicol, to the bioactive hydroxylamine species.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2020
Tipo de documento:
Article