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Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease.
Zhang, Liping; Wang, Ying; Dong, Yanlan; Chen, Zihong; Eckols, Thomas K; Kasembeli, Moses M; Tweardy, David J; Mitch, William E.
Afiliação
  • Zhang L; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas.
  • Wang Y; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas.
  • Dong Y; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas.
  • Chen Z; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas.
  • Eckols TK; Division of Internal Medicine, Department of Infectious Disease, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kasembeli MM; Division of Internal Medicine, Department of Infectious Disease, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tweardy DJ; Division of Internal Medicine, Department of Infectious Disease, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Mitch WE; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Am J Physiol Renal Physiol ; 319(1): F84-F92, 2020 07 01.
Article em En | MEDLINE | ID: mdl-32475130
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Sulfonamidas / Músculo Esquelético / Inibidores Enzimáticos / Insuficiência Renal Crônica / Fator de Transcrição STAT3 / Proteólise / Naftóis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Renal Physiol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Sulfonamidas / Músculo Esquelético / Inibidores Enzimáticos / Insuficiência Renal Crônica / Fator de Transcrição STAT3 / Proteólise / Naftóis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Renal Physiol Ano de publicação: 2020 Tipo de documento: Article