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Vitamin C in Health and Disease: A Companion Animal Focus.
Gordon, Daniel S; Rudinsky, Adam J; Guillaumin, Julien; Parker, Valerie J; Creighton, Karina J.
Afiliação
  • Gordon DS; Departments of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus OH, USA.
  • Rudinsky AJ; Departments of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus OH, USA.
  • Guillaumin J; Departments of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus OH, USA.
  • Parker VJ; Departments of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus OH, USA.
  • Creighton KJ; Departments of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus OH, USA. Electronic address: karinacreighton@gmail.com.
Top Companion Anim Med ; 39: 100432, 2020 Jun.
Article em En | MEDLINE | ID: mdl-32482285
Vitamin C is synthesized in the liver in most species, including dogs and cats, and is widely distributed through body tissues. Vitamin C has an important physiologic role in numerous metabolic functions including tissue growth and maintenance, amelioration of oxidative stress, and immune regulation. It is also a co-factor in the production of important substances such as catecholamines and vasopressin. Decreased vitamin C levels have been documented in a wide variety of diseases, and in critically ill human patients may be associated with increased severity of disease and decreased survival. Intravenous supplementation with vitamin C has been proposed as a potential life-saving treatment in conditions such as septic shock, and results of small some human trials are promising. Data in companion in animals is very limited, but the possible benefits and , seemingly low risk of adverse effects , and the low cost of this treatment make vitamin C therapy a promising area of future investigation in critically ill dogs and cats.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Ascórbico / Doenças do Gato / Doenças do Cão Limite: Animals Idioma: En Revista: Top Companion Anim Med Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Ascórbico / Doenças do Gato / Doenças do Cão Limite: Animals Idioma: En Revista: Top Companion Anim Med Ano de publicação: 2020 Tipo de documento: Article