Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.

Ren, Liting; Feng, Wenya; Shao, Jie; Ma, Juan; Xu, Ming; Zhu, Ben-Zhan; Zheng, Nanfeng; Liu, Sijin

Ren, Liting; Feng, Wenya; Shao, Jie; Ma, Juan; Xu, Ming; Zhu, Ben-Zhan; Zheng, Nanfeng; Liu, Sijin.

Afiliação

Ren L; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Feng W; State Key Laboratory for Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, and National & Local Joint Engineering Research Center for Preparation Technology of Nanomaterials, College of Chemistry and Chemical Engineering, Xiamen University,
Shao J; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Ma J; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xu M; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Zhu BZ; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zheng N; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Liu S; University of Chinese Academy of Sciences, Beijing, 100049, China.

Theranostics ; 10(14): 6384-6398, 2020.

Article em En | MEDLINE | ID: mdl-32483459

Assuntos

Antineoplásicos/farmacologia; Cobre; Dissulfiram; Ditiocarb; Nanopartículas; Animais; Antineoplásicos/química; Neoplasias da Mama/tratamento farmacológico; Linhagem Celular Tumoral/efeitos dos fármacos; Núcleo Celular; Cobre/química; Cobre/farmacologia; Dissulfiram/química; Dissulfiram/farmacologia; Ditiocarb/química; Ditiocarb/farmacologia; Sistemas de Liberação de Medicamentos; Liberação Controlada de Fármacos; Reposicionamento de Medicamentos; Feminino; Humanos; Terapia com Luz de Baixa Intensidade; Camundongos; Nanomedicina; Nanopartículas/química; Nanopartículas/uso terapêutico; Metástase Neoplásica/tratamento farmacológico; Neoplasias/tratamento farmacológico; Nanomedicina Teranóstica/métodos

Palavras-chave

DSF-Cu nanocomplex; diethyldithiocarbamate; epithelial-mesenchymal transition; light-triggered nuclear targeting; metastasis

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Ditiocarb / Cobre / Dissulfiram / Nanopartículas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Theranostics Ano de publicação: 2020 Tipo de documento: Article

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